TB-500

Compound identity

Each row above is attributed to its source. Rows citing a database record are reference information about the molecule; rows marked catalog information describe this listing. Neither is a specification, an analytical result or a claim about any particular batch.

Research classification

Synthetic acetylated heptapeptide. Not an approved medicine.

Chemical characteristics

• At roughly 889 g/mol this is by a wide margin the smallest peptide in the catalog, and considerably smaller than intact thymosin beta-4 at around 5053 Da. Anything reported near 5 kDa is not this molecule.
• N-terminal acetylation caps the free amino group and adds approximately 42 Da relative to the unmodified heptapeptide. A mass observed about 42 Da low would suggest the acetyl group is absent.
• The sequence contains no cysteine, methionine or tryptophan, so it carries none of the usual oxidation liabilities and no disulfide chemistry to account for.
• With no tryptophan or tyrosine there is effectively no absorbance at 280 nm, so ultraviolet detection has to be run near 214 nm where the peptide bond absorbs. A purity figure quoted at 280 nm for this peptide would be meaningless.
• Two lysine residues and one glutamate make the peptide net-basic at neutral pH.

Analytical methods

• Reversed-phase HPLC (RP-HPLC) is the method most commonly used to express the chromatographic purity of a synthetic peptide as a percentage of total peak area at a stated wavelength.
• Mass spectrometry (typically ESI-MS or MALDI-TOF) is used to confirm that the observed mass of the material is consistent with the expected mass of the intended sequence.
• Because purity figures are method-dependent, an analytical result is only interpretable alongside the method conditions and the batch it describes.

Both methods are covered in more detail in our guides to HPLC analysis of peptides and mass spectrometry for identity confirmation.

Stability and storage considerations

• Lyophilized peptides are generally supplied as a dry solid because the removal of water slows hydrolytic degradation pathways.
• Cold, dry, light-protected storage is the general handling expectation for lyophilized research peptides.
• Once a peptide is taken into solution, its stability profile changes and is influenced by solvent, pH, temperature and the number of freeze-thaw cycles.
• Storage and handling expectations for a specific batch should be taken from that batch's documentation rather than from general guidance.

See peptide stability and degradation for the chemistry behind these considerations.

Independent Analytical Documentation

We do not currently publish a full independent analytical report on this page for the TB 500 listed here. That does not mean documentation is unavailable — it means the report is supplied on request for the batch being fulfilled, rather than attached permanently to a catalog listing that outlives any one batch.

If a report is a requirement for your work, ask before ordering. We will check what Janoshik or other documentation covers the current batch and tell you what it is. Where nothing exists for that batch, we will say so.

Reading the documentation matters as much as having it. Our guides on how to read a peptide certificate of analysis and what a purity figure does and does not mean cover what to look for, and our documentation page explains the request process.

Ordering TB 500 in India

TB 500 is ordered through the catalog and finalised over WhatsApp or email, so that any question about specification or documentation is settled before the order is placed rather than after it.

Immediate dispatch whenever couriers are operating. Orders from Bangalore are dispatched immediately whenever courier operations are open. Orders from elsewhere in India are dispatched as soon as couriers are operating.

Distribution is within India. Material is supplied for in-vitro research and analytical applications only, and we do not supply for human or veterinary use.

Frequently asked questions

Can I buy TB-500 in India from Peptide Tactics?

Yes. TB-500 is listed as a 10 mg lyophilized vial with the price shown on this page, available to order for research use within India. Given that the name is used for more than one molecule across the market, we would encourage reading the identity section on this page before ordering so that you know which chemical record the published reference data describes.

What documentation can I request for TB-500?

You can request whatever documentation exists for the batch being supplied, and we will tell you what that is before you order. Depending on the batch that may be a supplier certificate of analysis or an independent laboratory report. We do not hold a published independent analytical report for the TB-500 currently listed and do not claim one. Where documentation does not exist, we say so rather than implying it does.

How quickly are TB-500 orders dispatched?

Dispatch is immediate whenever courier services are operating. Bangalore orders take priority in the dispatch queue; orders from elsewhere in India go out as soon as couriers are running, and anything received outside courier hours is dispatched when they reopen. We do not quote a delivery date, because transit time is the courier's and not ours.

Can you source a peptide that is not listed?

Yes. Our catalog is what we currently hold, not the limit of what we can look into. Send the compound name, quantity and any specification that matters — salt form, purity threshold, documentation requirement — and we will investigate sourcing options and tell you what is possible, what it would cost and what documentation exists.

Is TB-500 intended for human use?

No. Everything in this catalog is supplied for in-vitro research and analytical applications only, and not for human or veterinary use. We do not provide dosing, administration guidance or any therapeutic recommendation, and we cannot supply material for those purposes.

What is the molecular weight of TB-500?

The PubChem record indexed under the name TB-500 (CID 62707662) gives a molecular formula of C38H68N10O14 and a molecular weight of 889.0 g/mol, with a monoisotopic mass of 888.49 Da. That describes the acetylated heptapeptide Ac-LKKTETQ-OH.

What is the sequence of TB-500?

The PubChem record gives LKKTETQ, written in full as Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln-OH. This motif also occurs within the thymosin beta-4 sequence.

Is TB-500 the same molecule as thymosin beta-4?

No. The PubChem TB-500 record is a seven-residue peptide of about 889 g/mol, whereas thymosin beta-4 is a 44-residue protein of about 5053 Da. The heptapeptide corresponds to a motif contained within thymosin beta-4, not to the whole protein. Some suppliers nevertheless use the name TB-500 for the full sequence, which is why batch documentation matters.

Does the Peptide Tactics batch match the PubChem TB-500 record?

We do not assert that it does. The reference data on this page describes the molecule indexed under that name in PubChem. Confirming what a specific batch actually contains requires that batch's documentation, or independent analysis.

What format is TB-500 supplied in?

The catalog entry is a 10 mg vial of lyophilized powder, consistent with the other peptide entries in this catalog.

Sources

• PubChem CID 62707662 — TB-500 (Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln-OH), CAS 885340-08-9
• UniProt P62328 — Thymosin beta-4 (human)

Related compounds

Further reading

• What are peptides? — A peptide is a chain of amino acids joined by amide bonds.
• Mass spectrometry and peptide characterisation — Chromatography tells you how many species are present.
• Understanding peptide certificates of analysis — A certificate of analysis is a record of what was measured on a specific batch.